Residual Symptoms of Depression: Adjuvant Therapies

Enrique Octavio Flores Gutiérrez, Víctor Andrés Terán Camarena, Jorge Julio González Olvera



Residual symptoms of depression (SRD) are those that persist despite a good response to antidepressant drug treatment. They have a high incidence in the psychiatric clinic and are significantly related to a high risk of relapse/recurrence. There are insufficient controlled studies to define a pharmacological treatment for the management of SRD, however, different long-term schemes have proven, nevertheless, that side effects involve a significant limitation. The aim of this review is to investigate and analyze the non-pharmacological treatment options for the management of the SRD. Only four type treatments were found: Cognitive Behavioral Therapy, Well-being Therapy, Mindfulness-Based Cognitive Therapy and Euthymic Therapy. The mentioned psychotherapeutic treatments reported decreased rates in relapse and/or clinimetric decreased in SRD levels.


Residual symptoms; depression; partial remission; psychotherapy; non-pharmacological treatment; relapse