Autism, the current pathological trend in psychiatry

Humberto Nicolini



In the past decade, autistic spectrum disorders (ASD) have received great attention from society, as well as funding for biomedical research. This has been reflected in the significant increase in scientific publications on the subject.


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Anagnostou, E., Soorya, L., Chaplin, W., Bartz, J., Halpern, D., Wasserman, S., … Hollander, E. (2012). Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Molecular Autism, 3(1), 16. doi: 10.1186/2040-2392-3-16

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Emerson, R. W., Adams, C., Nishino, T., Hazlett, H. C., Wolff, J. J., Zwaigenbaum, L., … Kandala, S. (2017) Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age. Science translational medicine, 9(393), eaag2882. doi: 10.1126/scitranslmed.aag2882

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Lombardo, M. V., Moon, H. M., Su, J., Palmer, T. D., Courchesne, E., & Pramparo, T. (2018). Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder. Molecular Psychiatry, 23(4), 1001-1013. doi: 10.1038/mp.2017.15

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Zeestraten, E. A., Gudbrandsen, M. C., Daly, E., de Schotten, M. T., Catani, M., Dell’Acqua, F., … Baron-Cohen, S. (2017). Sex differences in frontal lobe connectivity in adults with autism spectrum conditions. Translational Psychiatry, 7(4), e1090. doi: 10.1038/tp.2017.9